(Ebook) XIth International Symposium on Amyloidosis 1st edition by Martha Skinner, John Berk, Lawreen Connors, David Seldin 1040171431 9781040171431

(Ebook) XIth International Symposium on Amyloidosis 1st edition by Martha Skinner, John Berk, Lawreen Connors, David Seldin 1040171431 9781040171431

XIth International Symposium on Amyloidosis 1st edition by Martha Skinner, John L. Berk, Lawreen H. Connors, David C. Seldin - Ebook PDF Instant Download/DeliveryISBN:  1040171431, 9781040171431 

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ISBN-10 :  1040171431

ISBN-13 :  9781040171431

Author: Martha Skinner, John L. Berk, Lawreen H. Connors, David C. Seldin  

Edited by a stellar team of scientists compiling more than 120 papers into a single tome, the XIth Annual International Symposium on Amyloidosis represents the most important review of the state-of-the-science and future directions of the field. An unparalleled cast of pioneering researchers, including keynote speaker and Nobel Laureate, Dr. Stanley Prusiner, present groundbreaking research in systemic amyloidosis including the mechanisms of disease and cellular toxicity, AA amyloidosis, familial amyloidosis, AL amyloidosis, clinical trials, and emerging translational approaches. Focusing on new basic and translational medicine approaches in systemic amyloidosis, this book provides clinicians and researchers with an invaluable reference to the most up-to-date research in the field.

XIth International Symposium on Amyloidosis 1st Table of contents:

Outstanding Achievement Award
Symposium Keynote Address
Report of the Nomenclature Committee
SECTION I: MECHANISMS OF FIBRIL FORMATION AND
KEYNOTE ADDRESS:: THE EFFECT OF MEMBRANES AND SURFACES ON THE FIBRILLATION OF AN
HEPARAN SULFATE PROMOTES THE REFOLDING AND OLIGOMERIZATION OF SAA1.1:: A SHORT SEQUENCE IS IMPLICATED IN THIS MISFOLDING PROCESS
MOUSE SENILE AMYLOIDOSIS: POSSIBLE HORIZONTAL TRANSMISSION IN THE: MOUSE ROOM
CHARGE DIFFERENCES OF DEPOSITS IN AL AND NALCDD
ROLE OF THE C-TERMINAL AMINO ACIDS IN P2-MICROGLOBULIN AMYLOID FORMATION
SERUM AMYLOID A GENERATES HIGH-DENSITY LIPOPROTEIN FROM HUMAN AORTIC
AMYLOID LIGHT CHAINS LOCALIZE TO LYSOSOMES AND CARDIAC FIBROBLASTS SHOW REDUCED MITOCHONDRIAL FUNCTION
CEREBROSPINAL FLUID AND PLASMA OF ALZHEIMER PATIENTS PROMOTE p- AMYLOID FIBRIL FORMATION IN VITRO
A NOVEL ASSAY FOR DETECTION OF AMYLOID INDUCED APOPTOSIS
HUMAN AMYLOIDOGENIC IMMUNOGLOBULIN LIGHT CHAINS ALTER CARDIOMYOCYTE SIGNALING AND DISRUPT HEPARAN SULFATE PROTEOGLYCAN (HSPG) EXPRESSION
GAGS ASSOCIATED WITH FIBRIL EXTRACTS MEDIATE FIBRILLOGENESIS IN AL AMYLOIDOSIS
DECORIN IN AA AMYLOIDOSIS
STRUCTURAL EVOLUTION OF IMMUNOGLOBULIN LIGHT CHAIN DURING AMYLOID FIBRIL FORMATION: A DEEP UV RESONANCE RAMAN SPECTROSCOPIC STUDY
SECTION II: AA AND LOCALIZED AMYLOIDOSES
KEYNOTE ADDRESS:
HISTOCHEMICAL AND IMMUNOHISTOCHEMICAL CHARACTERISTICS OF AMYLOID DEPOSITS
ULTRASTRUCTURAL CHARACTERISTICS OF AMYLOID DEPOSITS
ODONTOGENIC FELINE AND CANINE TUMOR-ASSOCIATED AMYLOID IS FORMED FROM
AMYLOIDOGENIC REGION OF ODONTOGENIC AMELOBLAST ASSOCIATED PROTEIN
WHAT IS THE BEST WAY TO ASSESS PREDISPOSITION TO AA AMYLOID IN INFLAMMATORY JOINT DISEASE?
ADVANCES IN NON-INVASIVE IMAGING OF AA AMYLOID IN MICE
DETECTION AND IDENTIFICATION OF AMYLOID DEPOSITION ASSOCIATED WITH
VASCULAR AA AMYLOID FORMATION MODELED IN CELL CULTURE
AMYLOIDOSIS IN ANKYLOSING SPONDYLITIS - UNEXPECTED FINDINGS: UNDERSCORING THE IMPORTANCE OF TYPING OF AMYLOID DEPOSITS
LACK OF CORRELATION BETWEEN AMYLOID A PROTEIN LEVELS AND CLINICAL PARAMETERS IN ASPIRATED FAT TISSUE OF FAMILIAL MEDITERRANEAN FEVER PATIENTS WITH SECONDARY AMYLOIDOSIS
CHRONIC, SLOWLY PROGRESSING NEPHROPATHY DUE TO AMYLOIDOSIS OF CSAA (SAA4) ORIGIN
REDISTRIBUTION, CLEARANCE AND RE-INDUCTION OF AMYLOID IN REACTIVE MURINE
N-FORMYL PEPTIDE RECEPTOR-LIKE 1 OF THE NEUTROPHILS IN THE AA-: AMYLOIDOSIS TISSUES IS LESS STAINED
AL IN THE CLINICAL SETTING OF AA: THE IMPORTANCE OF AMYLOID TYPING
FOIE GRAS IS A DIETARY SOURCE OF AEF
THE EFFECT OF A VARIETY OF ANTI-INFLAMMATORY DRUGS ON MURINE AMYLOIDOGENESIS
TRANSLOCATION OF SYSTEMIC AMYLOIDOSIS BY PERIPHERAL BLOOD MONOCYTES
FK506 INHIBITS MURINE AA AMYLOIDOSIS WITHOUT MODULATING SERUM SAA LEVELS
LOCAL TUMOROUS AA-AMYLOID DEPOSITION IN A CASE OF HEPATIC
SAA4-RELATED AA AMYLOIDOSIS
MEASUREMENT OF AMYLOIDOGENIC SAA ISOTYPE, SAA1
SECTION III: FAMILIAL AND TTR AMYLOIDOSES
IN VITRO AND IN VIVO EFFECTS OF GENISTEIN ON TTR STABILIZATION AND AGGREGATION
LABIAL SALIVARY GLAND BIOPSY FOR DIAGNOSIS OF AMYLOID
HEREDITARY GELSOLIN AMYLOIDOSIS IN AN IRANIAN FAMILY: THE FIRST REPORT
A CASE OF COMPOUND HETEROZYGOSITY IN A NIGERIAN MALE WITH IDENTIFICATION
SUPPRESSION OF HEPATIC TRANSTHYRETIN SYNTHESIS BY ANTISENSE
TOP-DOWN MASS SPECTROMETRY ANALYSIS OF AMYLOIDOGENIC PROTEINS
ATTR (THR59LYS) AMYLOIDOSIS WITH INVOLVEMENT OF HEART, PERIPHERAL AND AUTONOMIC NERVOUS SYSTEM, GUT AND SALIVARY GLANDS IN AN EGYPTIAN MAN, PREVIOUSLY DIAGNOSED AS “FAMILIAL AMYLOID NEUROPATHY OF PORTUGUESE TYPE”
SYSTEMIC AMYLOIDOSIS OF FIBRINOGEN ORIGIN IN THE WILD LIVING STONE
FAMILIAL AMYLOID NEPHROPATHY OF FIBRINOGEN Aa (E526V) ORIGIN. REPORT OF THE FIRST CASE FROM AUSTRIA
LARYNGEAL AMYLOIDOSIS IN PATIENTS WITH APOLIPOPROTEIN AI L174S AND L178P
HEREDITARY FIBRINOGEN A a-CHAIN AMYLOIDOSIS: CLINICAL FEATURES AND
AMYLOIDOSIS IN THE TRANSGENIC MICE OF MOUSE AMYLOIDOGENIC APOLIPOPROTEIN A-II (APOA2C)
URINARY TRANSTHYRETIN: A POSSIBLE BIOCHEMICAL MARKER IN THE EARLY STAGE OF RENAL DYSFUNCTION
UNIQUE PHENOTYPE OF VITREOUS AMYLOIDOSIS IN DIFFERENT ENDEMIC AREAS
COMPOSITION OF PERIPHERAL NERVE AMYLOID AFTER ORTHOTOPIC LIVER
CHARACTERIZATION OF FIBRILLAR TRANSTHYRETIN IN EX VIVO CARDIAC DEPOSITS FROM CASES OF SENILE SYSTEMIC AMYLOIDOSIS
COMPARISON OF CARDIAC AMYLOIDOSIS ASSOCIATED WITH WILD TYPE TRANSTHYRETIN AND THE ISOLEUCINE 122 VARIANT
BIOCHEMICAL CHARACTERIZATION OF LEPTOMENINGEAL AMYLOID IN A VAL30GLY TRANSTHYRETIN PATIENT
APOLIPOPROTEIN A-I (APO A-I) NATURE OF KNEE JOINT MENISCUS-ASSOCIATED AMYLOID
AN AUTOPSY CASE OF FAMILIAL AMYLOIDOTIC POLYNEUROPATHY ATTR VAL30MET 10 YEARS AFTER LIVER TRANSPLANTATION: CHANGES IN THE AMOUNT OF AMYLOID DEPOSITS IN THE PANCREAS
AMYLOID NEUROPATHY IN A JAPANESE DOMINO LIVER-TRANSPLANTED RECIPIENT
THE NATURAL HISTORY OF HEREDITARY APOLIPOPROTEIN A-I AMYLOIDOSIS
DOMINO LIVER TRANSPLANTATION USING THE EXPLANTED GRAFTS FROM PATIENTS WITH HEREDITARY FORMS OF AMYLOIDOSIS: THE KING’S COLLEGE HOSPITAL EXPERIENCE
CARDIOMYOPATHY IN FAP VAL30MET PATIENTS WITH AND WITHOUT LIVER
DETECTION OF CARDIAC PRE-AMYLOID DEPOSITS OF TRANSTHYRETIN BY MALDI-TOF
EFFECT OF NITRIC OXIDE IN TRANSTHYRETIN-RELATED AMYLOIDOSIS
INHIBITION OF INTRACELLULAR TETRAMERIZATION INDUCES THE PROTEASOMAL DEGRADATION OF AMYLOIDOGENIC TRANSTHYRETIN VARIANTS
STRUCTURAL ANALYSES OF FIBRINOGEN Aa-CHAIN AMYLOID FIBRILS
A TRANSTHYRETIN MUTATION (V32A) IN AN ISRAELI PATIENT WITH AMYLOIDOTIC
AMYLOID DEPOSITION IN THE TONGUE OF PATIENTS WITH FAMILIAL AMYLOIDOTIC POLYNEUROPATHY
RECENT NOVEL AND RARE MUTATIONS IN A CLINIC POPULATION OF PATIENTS WITH AMYLOIDOSIS
PROLIFERATION OF SMOOTH MUSCLE CELLS IN THE TUNICA INTIMA OF CEREBRAL VESSELS IN FAMILIAL AMYLOIDOTIC POLYNEUROPATHY ATTR Y114C
REENGINEERING TTR AMYLOID INHIBITION PROPERTIES OF DIFLUNISAL
FAMILIAL AMYLOIDOSIS ASSOCIATED WITH A NOVEL MUTATION (D68G) IN THE
EFFECTS OF LIVER TRANSPLANTATION ON HEREDITARY CEREBRAL AMYLOID ANGIOPATHY ASSOCIATED WITH ATTR Y114C
EFFECT OF TACROLIMUS AND CYCLOSPORINE ON TRANSTHYRETIN (TTR) METABOLISM IN RATS: A LONG TERM ANALYSIS
SECTION IV: AL AMYLOIDOSIS
KEYNOTE ADDRESS:
IDENTIFICATION OF NOVEL INHIBITORS OF LIGHT CHAIN FIBRILLOGENESIS
PEPTIDE PHAGE DISPLAY AND EPITOPE MAPPING OF A FIBRIL-RELATED
THE TRANSLOCATION T(11;14) IS FREQUENTLY DETECTED IN PATIENTS WITH AL AMYLOIDOSIS
ALBASE: A PLATFORM ANALYSIS TOOL FOR THE STUDY OF AMYLOID LIGHT CHAIN SEQUENCE DATA
RISK-ADAPTED MELPHALAN WITH STEM CELL TRANSPLANT (SCT) AND ADJUVANT DEXAMETHASONE (DEX) +/- THALIDOMIDE (THAL) ACHIEVES LOW TREATMENT- RELATED MORTALITY AND HIGH HEMATOLOGIC RESPONSE RATES
A SUPERVISED ANALYSIS OF GENE-EXPRESSION PROFILES OF PURIFIED CLONAL
COMPARISON OF IMMUNOGLOBULIN LIGHT CHAINS (K1): AMYLOIDOGENIC VS. NON- AMYLOIDOGENIC PROTEINS
CLINICOPATHOLOGICAL ANALYSIS OF THIRTY-TWO PATIENTS WITH AL AMYLOIDOSIS:
ROLE OF LIGHT CHAIN DEAMIDATION IN THE PATHOGENESIS OF AL AMYLOIDOSIS
THE EXTENT AND DISTRIBUTION OF AMYLOID IN 38 AUTOPSIES ON PATIENTS WITH
TRANSPLANTATION WITHOUT GROWTH FACTOR ENGRAFTMENT KINETICS
EXTENT OF HEMATOLOGIC RESPONSE IS IMPORTANT IN DETERMINING OUTCOME IN
A SINGLE-CENTER EXPERIENCE USING CHEMOTHERAPY WITH MELPHALAN- DEXAMETHASONE (M-DEX) IN PATIENTS WITH AL AMYLOIDOSIS AND ADVANCED ORGAN INVOLVEMENT NOT ELIGIBLE FOR HIGH-DOSE MELPHALAN THERAPY (HDM)
DETECTION AND CHARACTERIZATION OF AL LIGHT CHAIN PROTEINS FROM FIBRILS
CHARACTERIZATION OF POST-TRANSLATIONAL MODIFICATIONS OF AN AMYLOIDOGENIC IMMUNOGLOBULIN KAPPA LIGHT CHAIN BY MASS SPECTROMETRY
INVOLVEMENT OF LYSOSOMES IN RENAL AL-AMYLOIDOGENESIS
THERMAL UNFOLDING OF IMMUNOGLOBULIN LIGHT CHAINS IS LINKED TO AGGREGATION: CIRCULAR DICHROISM AND LIGHT SCATTERING STUDIES
PROGNOSTIC RELEVANCE OF SERUM N-TERMINAL PRONATRIURETIC PEPTIDE TYPE B AND PLASMA BNP IN PATIENTS WITH AL AMYLOIDOSIS IN DIALYSIS
AL AMYLOIDOSIS IN THE ELDERLY: A REVIEW OF 330 PATIENTS
THERAPEUTIC POTENTIAL OF NATURALLY OCCURRING FIBRIL-REACTIVE HUMAN
PROLONGED FOLLOW-UP STUDY OF AL PATIENTS INELIGIBLE FOR STEM CELL TRANSPLANTATION TREATED WITH ORAL MELPHALAN AND DEXAMETHASONE
LEFT VENTRICULAR SYSTOLIC FUNCTION IN PATIENTS WITH CARDIAC AL
IN VITRO SILENCING OF AMYLOIDOGENIC À6 LIGHT CHAIN PRODUCTION
AMYLOID TYPING IN SURGICAL PATHOLOGY: EXPERIENCE OF A SINGLE INSTITUTION
SOMATIC MUTATIONS CREATE POTENTIAL W-GLYCOSYLATION SITES IN THE IMMUNOGLOBULIN LIGHT CHAIN VARIABLE REGIONS IN PRIMARY AMYLOIDOSIS
A TRIAL OF ANTIOXIDANTS TO IMPROVE CARDIAC FUNCTION IN PATIENTS WITH AL AMYLOIDOSIS AND CARDIAC INVOLVEMENT
HIGH-DOSE MELPHALAN CHEMOTHERAPY WITH AUTOLOGOUS STEM CELL
GLYCOSYLATED AMYLOID AND NON-AMYLOID ASSOCIATED LAMBDA LIGHT CHAINS
EXTRAMEDULLARY PRODUCTION OF AL AMYLOID PRECURSOR PROTEIN
MESANGIAL AMYLOID FORMATION IN AN ISOLATED RAT KIDNEY PERFUSION MODEL:
OVEREXPRESSION OF CALRETICULIN IN CLONAL AL PLASMA CELLS IS ASSOCIATED
SEMI-QUANTITATIVE ASSESSMENT OF AMYLOID IN CONGO RED-STAINED
IMAGING HUMAN AL AMYLOID IN MICE USING THE FIBRIL-REACTIVE MONOCLONAL
TANDEM MASS SPECTROMETRY AND OTHER METHODS IDENTIFY APOLIPOPROTEIN
MOUSE MODELS OF AL AMYLOIDOSIS
NT-PROBNP IN AL AMYLOIDOSIS: ASSOCIATION WITH SURVIVAL AND CHANGES
HISTOCHEMICAL-BASED STAGING SYSTEM FOR AL AMYLOIDOSIS
LOCALIZED AL AMYLOIDOSIS: A DISTINCTIVE CLINICOPATHOLOGIC DISORDER
EVALUATION OF PLASMA CELL VOLUME AND CLONALITY IN AL (PRIMARY)
BIOCHEMICAL CHARACTERIZATION OF AMYLOID FROM A RECTAL AMYLOIDOMA
SECTION V: NEW DIAGNOSTICS AND EMERGING TRANSLATIONAL APPROACHES
KEYNOTE ADDRESS:
THE DIAGNOSIS OF AMYLOIDOSIS MAY BE HINDERED BY THE SAMPLING ERROR,
SERUM AMYLOID P COMPONENT (SAP) CONCENTRATION IN ABDOMINAL FAT ASPIRATES OF PATIENTS WITH AMYLOIDOSIS
BIOCHEMICAL CHARACTERIZATION OF AMYLOID BY ENDOMYOCARDIAL BIOPSY
A PEPTIDE-BASED VACCINE ELICITS CTL RESPONSES TOWARDS AL AMYLOID-
DIAGNOSTIC ACCURACY AND PROGNOSTIC VALUE OF 123I-LABELED SERUM AMYLOID P COMPONENT BODY RETENTION IN PATIENTS WITH AMYLOIDOSIS
A PROTEOMIC APPROACH TO THE STUDY OF SYSTEMIC AMYLOIDOSES
DEFINITIVE IDENTIFICATION OF AMYLOID DEPOSITS BY MASS SPECTROMETRY
TISSUE DETECTION OF AMYLOID BY AN AMYLOID “CHIP”?
DETECTION AND CHARACTERIZATION OF IMMUNOGLOBULIN LIGHT CHAIN POST- TRANSLATIONAL MODIFICATIONS USING LC/MS-MS/MS
THE INHIBITORY Fcy-RECEPTOR IIB (CD32B) IS HIGHLY EXPRESSED ON CLONAL PLASMA CELLS FROM PATIENTS WITH SYSTEMIC LIGHT-CHAIN (AL) AMYLOIDOSIS AND PROVIDES A TARGET FOR MONOCLONAL ANTIBODY THERAPY
SECTION VI: CLINICALSESSIONS
REPORT FROM THE DIAGNOSTIC INTERACTIVE SESSION
REPORT FROM THE CLINICAL INTERACTIVE SESSION
CLINICAL TRIAL FOR TTR AMYLOIDOSIS USING DIFLUNISAL
EARLY HARVEST FOLLOWED BY MELPHALAN-DEXAMETHASONE AND SECOND-LINE
TREATMENT OF AL AMYLOIDOSIS WITH TANDEM CYCLES OF HIGH DOSE MELPHALAN

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