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(Ebook) Therapeutic Fc-Fusion Proteins by Steven M. Chamow, Thomas Ryll, Henry B. Lowman, Deborah Farson ISBN 9783527333172, 9783527675272, 3527333177, 3527675272

  • SKU: EBN-4724318
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Authors:Steven M. Chamow, Thomas Ryll, Henry B. Lowman, Deborah Farson
Pages:400 pages.
Year:2014
Editon:1
Publisher:Wiley-Blackwell
Language:english
File Size:7.36 MB
Format:pdf
ISBNS:9783527333172, 9783527675272, 3527333177, 3527675272
Categories: Ebooks

Product desciption

(Ebook) Therapeutic Fc-Fusion Proteins by Steven M. Chamow, Thomas Ryll, Henry B. Lowman, Deborah Farson ISBN 9783527333172, 9783527675272, 3527333177, 3527675272

Edited by three pioneers in the field – each with longstanding experience in the biotech industry – and a skilled scientific writer, this is the first book to cover every step in the development and production of immunoglobulin Fc-fusion proteins as therapeutics for human disease: from choosing the right molecular design, to pre-clinical characterization of the purified product, through to batch optimization and quality control for large-scale cGMP production.

The whole of the second part is devoted to case studies of Fc-fusion proteins that are now commercially successful products. In this section, the authors, several of whom were personally involved in clinical development of the products themselves, detail the product’s background and give insight into issues that were faced and how these issues were overcome during clinical development. This section also includes a chapter on promising new developments for the future.

An invaluable resource for professionals already working on Fc-fusion proteins and an excellent and thorough introduction for physicians, researchers, and students entering the field.

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