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(Ebook) Single Nucleotide Polymorphisms: Methods and Protocols by Pui-Yan Kwok ISBN 9780896039681, 0896039684

  • SKU: EBN-1618534
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Authors:Pui-Yan Kwok
Pages:283 pages.
Year:2002
Editon:1
Publisher:Humana Press
Language:english
File Size:4.51 MB
Format:pdf
ISBNS:9780896039681, 0896039684
Categories: Ebooks

Product desciption

(Ebook) Single Nucleotide Polymorphisms: Methods and Protocols by Pui-Yan Kwok ISBN 9780896039681, 0896039684

Pui-Yan Kwok, MD, PhD, has assembled a comprehensive collection of readily reproducible techniques for the difficult process of single nucleotide polymorphisms (SNP) discovery and genotyping. These cutting-edge protocols for mutation/SNP detection utilize denaturing high-performance liquid chromatography (dHPLC), single-strand conformation polymorphism (SSCP), conformation-sensitive gel electrophoresis (CSGE), chemical cleavage, and direct sequencing. Equally powerful and up-to-date methods are given for genotyping SNPs, including molecular beacons, the Taqman assay, single-base extension approaches, pyrosequencing, ligation, the Invader assay, and primer extension with mass spectrometry detection.
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