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10 reviewsThe articles cover nine areas of research with particular attention to four groups of extraordinary discoveries for which Snyder is widely recognized: the identification of opiate receptors, characterization of the IP3 receptor, the establishment of nitric oxide as a transmitter in the brain, and the discovery that D-serine is the normal stimulus for the glycine site of the NMDA receptor. Each section is accompanied by a commentary by a well-known authority that puts the discoveries in perspective. Together, they attest to the rich diversity of Snyder s research while conveying the origins of modern psychopharmacologic practice.