(Ebook) Recent Advances in Otolaryngology 8 1st Edition by David Moffat, James Keir, Holer Sudhoff ISBN 1853157112 9781853157110

(Ebook) Recent Advances in Otolaryngology 8 1st Edition by David Moffat, James Keir, Holer Sudhoff ISBN 1853157112 9781853157110

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ISBN 10: 1853157112
ISBN 13: 9781853157110
Author: David Moffat, James Keir, Holer Sudhoff

(Ebook) Recent Advances in Otolaryngology 8 1st Edition Table of contents:

1. MRI of Cholesteatoma
    – CT Imaging of Cholesteatoma
    – MRI of Cholesteatoma
    – MRI of Congenital Cholesteatoma
    – MRI of Acquired Cholesteatoma
    – MRI of Postoperative Cholesteatoma
    – MRI of Primary Bony Obliteration Techniques
    – MRI Protocol
    – Conclusions

2. Bacterial Biofilm Infections in Otology
    – Biofilm Development
    – Attachment
    – Growth of Colonies
    – Detachment and Release of Planktonic Cells
    – Survival Mechanisms Within Biofilms
     • Physical Barriers
     • Antibiotic Sequestration and Disruption
     • Altered Growth Rate or Persister Cells
     • Exchange of Genetic Material
     • Release or Reseeding
     • Novel Mechanisms
    – Biofilms in Otitis Media
    – Biofilms in Infected Cholesteatoma
    – Biofilms and Middle Ear Implant Infections
    – Biofilms in Chronic Osteoradionecrosis
    – Treatment Strategies for Bacterial Biofilms
    – Conclusions

3. Auditory Midbrain Implant: Experimental and Clinical Results
    – The Inferior Colliculus
    – Auditory Midbrain Implant
    – Electrophysiological Feasibility
    – Histomorphological Effects
    – Surgical Approach
    – Clinical Findings in the First Three Patients
    – Surgical Results
    – Psychophysical Results
    – Speech Results
    – Summary

4. Bilateral Cochlear Implantation
    – Binaural Hearing
    – Spatial Hearing
     • Interaural Level and Time Differences
     • Head Shadow Effect
     • Location of Sound Sources
     • Precedence Effect
    – Improved Hearing in Noise (BMLD, BILD)
    – Cocktail Party Phenomenon
    – Auditory Pattern Recognition
    – Bilateral Cochlear Implantation
     • History
     • Improved Speech Understanding
     • Re-establishing Spatial Hearing
     • After Meningitis
     • Simultaneous or Sequential Implantation
     • Timing Considerations
     • Contraindications
    – Ethical, Economic and Legal Considerations
    – Conclusions

5. Squamous Cell Carcinoma of the Temporal Bone
    – Aetiology
    – Epidemiology
    – Peak Incidence
    – Clinical Symptoms and Signs
    – Patterns of Spread
    – Management
     • Diagnosis and Investigations
     • Staging
     • Treatment: Radiotherapy and Surgery
     • Reconstruction and Complications
    – Prognosis and Prognostic Factors
     • Nodal Disease
     • Histology
     • Margins, Dural and Cerebral Involvement
     • Carotid Invasion
    – De Novo vs Salvage Surgery
    – Radiation-Associated Tumour
    – The Future

6. Reflux and Otitis Media with Effusion
    – Definitions and Classifications (GER, GERD, EER, EERD)
    – Otitis Media and Effusion
    – Aetiology and Prevalence
    – Pathogenesis of GER/EER
    – Protective and Pathological Mechanisms
    – Risk Factors
    – Eustachian Tube Dysfunction
    – Mechanism of Effusion
    – Reflux as a Contributing Factor
    – Symptoms and Clinical Features
    – Diagnosis and Diagnostic Tools
    – Therapy and Antireflux Treatment
    – Conclusions

7. Proteomics and Genomics of Head and Neck Squamous Cell Carcinoma
    – Proteomics
     • Expression Profiling
     • Comparison of Proteomes
     • Clinical Applications
     • Prognosis and Treatment Response
    – Genomics
     • DNA Microarrays
     • Molecular Classification
     • Targeted Therapies
    – Conclusions

8. Vaccines and Immunotherapy in Head and Neck Cancer
    – Immunotherapy Overview
    – Tumour Vaccines
    – HPV and HNSCC
    – HPV Vaccination
    – Dendritic Cell-Based Therapies
    – Epstein–Barr Virus and Nasopharyngeal Carcinoma
    – Adoptive Immunotherapies
    – Conclusions
    – Acknowledgements

9. Chemoradiotherapy for Head and Neck Cancer
    – Chemoradiotherapy and Organ Preservation
    – Cytotoxic Agents
    – Radiotherapy Schedule Improvements
    – Postoperative Chemoradiation
    – Lymph Node Dissection
    – Imaging After Treatment
    – Induction Chemotherapy
    – Novel Agents
    – Radiotherapy Advances
     • 3D Conformal Radiotherapy
     • Intensity-Modulated Radiotherapy
    – Conclusions

10. Image-Guided Surgery in Paranasal Sinus and Skull Base Surgery
     – Accuracy
     – CT–MRI Fusion
     – Intra-operative Updates
     – Tracking Systems
     – Conclusions

11. Questioning the Prevalence of Chronic Rhinosinusitis
     – Diagnostic Challenges
     – Midfacial Segment Pain
     – Conclusions

12. New Treatments in Recurrent Respiratory Papillomatosis
     – Surgical Options
      • Laser Surgery
      • Microdebrider
      • Tracheostomy
     – Anaesthesia and Care
     – Adjuvant Therapies
      • GER Control
      • Cidofovir, Interferon, Ribavirin, Acyclovir
      • Photodynamic Therapy
      • Indole-3-Carbinol
      • Heat Shock Proteins
      • Mumps Vaccine
     – HPV Vaccination
     – Current Strategies
     – Conclusions

Index

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