(Ebook) Protein Kinases as Drug Targets (Methods and Principles in Medicinal Chemistry 49) by Bert Klebl, Gerhard Müller, Michael Hamacher, Raimund Mannhold, Hugo Kubinyi, Gerd Folkers ISBN 3527317902

(Ebook) Protein Kinases as Drug Targets (Methods and Principles in Medicinal Chemistry 49) by Bert Klebl, Gerhard Müller, Michael Hamacher, Raimund Mannhold, Hugo Kubinyi, Gerd Folkers ISBN 3527317902

This timely guide to kinase inhibitor drug discovery is the first to cover the entire drug pipeline, from target identification to compound development and clinical application. Edited by pioneers in the field, on the drug development side this ready reference discusses classical medicinal chemistry approaches as well as current chemical genomics strategies. On the clinical side, both current and future therapeutic application areas for kinase inhibitor drugs are addressed, with a strong focus on oncology drugs.Backed by recent clinical experience with first-generation drugs in the battle against various forms of cancer, this is crucial reading for medicinal, pharmaceutical and biochemists, molecular biologists, and oncologists, as well as those working in the pharmaceutical industry.