(Ebook) Principles of virology 4th Edition by Lynn W Enquist, S Jane Flint, Anna Marie Skalka, Vincent R Racaniello, Glenn F Rall ISBN 1555819524 9781555819521

(Ebook) Principles of virology 4th Edition by Lynn W Enquist, S Jane Flint, Anna Marie Skalka, Vincent R Racaniello, Glenn F Rall ISBN 1555819524 9781555819521

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Product details:

ISBN 10: 1555819524 
ISBN 13: 9781555819521
Author: Lynn W Enquist, S Jane Flint, Anna Marie Skalka, Vincent R Racaniello, Glenn F Rall

Principles of Virology is the leading virology textbook because it does more than collect and present facts about individual viruses. Instead, it facilitates an understanding of basic virology by examining the shared processes and capabilities of viruses. Using a set of representative viruses to present the complexity and diversity of a myriad of viruses, this rational approach enables students to understand how reproduction is accomplished by known viruses and provides the tools for future encounters with new or understudied viruses.

This fully updated edition represents the rapidly changing field of virology. A major new feature is the inclusion of 26 video interviews with leading scientists who have made significant contributions to the field of virology.

(Ebook) Principles of virology 4th Table of contents:

Volume 1: Molecular Biology

• Preface

• About the Authors

• Part I: The Science of Virology

  • Chapter 1: The First Principles

    • Introduction to Viruses

    • Virus Discovery and Early Concepts

    • The Viral World: Diversity and Classification

  • Chapter 2: The Infectious Cycle

    • Overview of Viral Replication Strategies

    • Attachment and Entry

    • Genome Replication and Gene Expression

    • Assembly and Release

• Part II: Molecular Biology of Viral Life Cycles

  • Chapter 3: Principles of Virus Structure

    • Capsid Assembly

    • Enveloped Viruses

    • Structural Proteins and Their Functions

  • Chapter 4: Principles of Virus Entry

    • Receptor Binding

    • Membrane Fusion and Entry Pathways

    • Cellular Factors in Entry

  • Chapter 5: RNA-Dependent RNA Synthesis and Genome Replication

    • Mechanisms of RNA Replication

    • Positive-Sense RNA Viruses

    • Negative-Sense RNA Viruses

    • Double-Stranded RNA Viruses

  • Chapter 6: Reverse Transcription and Integration: Retroviruses

    • Life Cycle of Retroviruses

    • Reverse Transcriptase

    • Integration of Viral DNA

  • Chapter 7: Transcription, RNA Processing, and DNA Replication

    • Eukaryotic Transcription and RNA Splicing

    • DNA Virus Replication Strategies

    • Host Factors in DNA Virus Replication

  • Chapter 8: Protein Synthesis and Processing

    • Viral Strategies for Protein Synthesis

    • Post-Translational Modifications

    • Viral Proteases

  • Chapter 9: Assembly, Exit, and Maturation

    • Assembly Pathways of Nonenveloped Viruses

    • Assembly of Enveloped Viruses

    • Budding and Release

    • Maturation Cleavages

• Part III: Regulation and Manipulation of Viral Gene Expression

  • Chapter 10: Principles of Regulation

    • Temporal Control of Gene Expression

    • Transcriptional and Post-Transcriptional Regulation

    • Viral Strategies for Host Shutoff

  • Chapter 11: DNA Viruses

    • Specific Regulatory Mechanisms in Adenoviruses, Herpesviruses, Polyomaviruses

  • Chapter 12: RNA Viruses

    • Specific Regulatory Mechanisms in Influenza Virus, Poliovirus, HIV

• Part IV: Evolution and Genetics

  • Chapter 13: Viral Evolution

    • Mechanisms of Viral Evolution (Mutation, Recombination, Reassortment)

    • Quasispecies Concept

    • Viral Phylogeny

  • Chapter 14: Viral Genetics

    • Forward and Reverse Genetics

    • Mutagenesis

    • Complementation and Recombination Assays

Volume 2: Pathogenesis and Control

• Part V: Virus-Host Interactions

  • Chapter 15: Introduction to Viral Pathogenesis

    • Routes of Entry and Local Spread

    • Dissemination in the Host

    • Cellular Tropism and Pathogenesis

    • Factors Influencing Disease Outcome

  • Chapter 16: Patterns of Infection

    • Acute Infections

    • Persistent Infections (Latent, Chronic, Slow)

    • Transformation and Oncogenesis

  • Chapter 17: Viral Disease

    • Specific Examples of Viral Diseases and Their Pathogenesis

    • Factors Affecting Disease Severity

  • Chapter 18: The Immune System and Viral Evasion

    • Innate Immunity to Viruses

    • Adaptive Immunity to Viruses (Humoral and Cell-Mediated)

    • Viral Strategies to Evade Immune Responses

  • Chapter 19: Vaccines and Antivirals

    • Principles of Vaccination

    • Types of Vaccines

    • Antiviral Drug Discovery and Mechanisms

    • Drug Resistance

  • Chapter 20: Epidemiology and Control of Viral Diseases

    • Principles of Epidemiology

    • Transmission Routes

    • Surveillance and Outbreak Investigation

    • Public Health Interventions

• Part VI: Special Topics in Virology

  • Chapter 21: Prions

    • Nature of Prions

    • Prion Diseases (e.g., CJD, BSE)

    • Mechanisms of Prion Propagation

  • Chapter 22: Emerging Viruses

    • Factors Contributing to Emergence

    • Examples of Emerging Viruses (e.g., Ebola, SARS, MERS, Zika)

    • Preparedness and Response

  • Chapter 23: Viral Vectors and Gene Therapy

    • Use of Viruses in Gene Therapy

    • Types of Viral Vectors

    • Safety and Efficacy Considerations

  • Chapter 24: Viruses and Cancer

    • Oncogenic Viruses (e.g., HPV, EBV, HBV)

    • Mechanisms of Viral Oncogenesis

  • Chapter 25: Viruses and the Future

    • Challenges and Opportunities in Virology Research

    • New Technologies and Approaches

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