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Periodontitis treatment and progression of carotid intima-media thickness: a randomized trial by Marco Orlandi & Stefano Masi & Ersilia Lucenteforte & Devina Bhowruth & Marco A. Malanima & Ulpee Darbar & Kalpesh Patel & Chong Lim & Chiara Curra & Tay Shiehfung & Jeanie Suvan & Scott T. Chiesa & John Deanfield & Francesco D’Aiuto instant download

  • SKU: EBN-238632740
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Instant download (eBook) Periodontitis treatment and progression of carotid intima-media thickness: a randomized trial after payment.
Authors:Marco Orlandi & Stefano Masi & Ersilia Lucenteforte & Devina Bhowruth & Marco A. Malanima & Ulpee Darbar & Kalpesh Patel & Chong Lim & Chiara Curra & Tay Shiehfung & Jeanie Suvan & Scott T. Chiesa & John Deanfield & Francesco D’Aiuto
Pages:updating ...
Year:2025
Publisher:x
Language:english
File Size:6.81 MB
Format:pdf
Categories: Ebooks

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Periodontitis treatment and progression of carotid intima-media thickness: a randomized trial by Marco Orlandi & Stefano Masi & Ersilia Lucenteforte & Devina Bhowruth & Marco A. Malanima & Ulpee Darbar & Kalpesh Patel & Chong Lim & Chiara Curra & Tay Shiehfung & Jeanie Suvan & Scott T. Chiesa & John Deanfield & Francesco D’Aiuto instant download

DOI: 10.1093/eurheartj/ehaf555; European Heart Journal, 2025-08-19.; Abstract: Background and Aims: Intensive periodontal treatment (IPT) improves endothelial function in patients with periodontitis (PD). However, whether these changes can slow the progression of structural vascular remodelling remains unclear. This randomized clinical trial evaluated the impact of IPT on carotid intima-media thickness (cIMT) over 2 years (NCT03072342). Flow-mediated dilatation (FMD), blood pressure and pulse wave velocity (PWV) were assessed as secondary outcomes, while markers of inflammation, oxidative stress, and metabolomics were explanatory outcomes. Methods: 135 consecutive, otherwise healthy participants with PD, were enrolled in a single-blind, single-centre, controlled trial, and randomized to IPT (n = 68; including scaling, root planning, and, when appropriate, surgical corrective therapy) or control periodontal treatment (CPT, n = 67; including supra-gingival scaling and polishing). cIMT
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