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(Ebook) Nuclear Receptors in Drug Metabolism 1st Edition by Wen Xie ISBN 9780470086797 0470086793

  • SKU: EBN-1800612
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Authors:Wen Xie
Pages:338 pages.
Year:2008
Editon:1
Publisher:Wiley
Language:english
File Size:4.65 MB
Format:pdf
ISBNS:9780470086797, 9780470409053, 0470086793, 0470409053
Categories: Ebooks

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(Ebook) Nuclear Receptors in Drug Metabolism 1st Edition by Wen Xie ISBN 9780470086797 0470086793

(Ebook) Nuclear Receptors in Drug Metabolism 1st Edition by Wen Xie - Ebook PDF Instant Download/Delivery: 9780470086797 ,0470086793
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Product details:

ISBN 10: 0470086793
ISBN 13: 9780470086797
Author: Wen Xie

This book gives you an updated and expert overview of nuclear hormone receptors in drug metabolism and drug development and equips you with the interdisciplinary understanding of these receptors and how they can be regulated. Pharmaceutical researchers will find this extremely useful in developing drugs for cancer, heart disease, and diabetes treatment. This comprehensive resource collects scattered materials into one handy, informative volume.
 

(Ebook) Nuclear Receptors in Drug Metabolism 1st Edition Table of contents:

  1. Drug metabolism : significance and challenges
  2. Establishing orphan nuclear receptors PXR and CAR as xenobiotic receptors
  3. Nuclear receptor-mediated regulation of phase II conjugating enzymes
  4. Nuclear receptor-mediated regulation of drug transporters
  5. Structure and function of PXR and CAR
  6. Xenobiotic receptor co-factors and co-regulators
  7. Animal models of xenobiotic nuclear receptors and their utility in drug development
  8. Nuclear receptors and drug-drug interactions of prescription drugs and herbal medicines
  9. Genetic variants of xenobiotic receptors and their implications in drug metabolism and pharmacogenetics
  10. Beyond PXR and CAR : xenobiotic regulation by other nuclear receptors
  11. The emerging role of retinoid-related orphan receptor (ROR) and its crosstalk with LXR in the regulation of drug metabolizing enzymes.

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Tags: Wen Xie, Nuclear Receptors, Drug Metabolism

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