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0 reviewsTracking no: BLD-2024-025875R2-ASojeong Kim (Yonsei University College of Medicine, Korea, Republic of) Jeong-Eun Kwak (YonseiUniversity College of Medicine, Korea, Republic of) June-Young Koh (Inocras, United States) Ji EunLee (Yonsei University College of Medicine, Korea, Republic of) Hye Won Kook (Yonsei UniversityCollege of Medicine, Korea, Republic of) Minchae Kim (DGIST, Korea, Republic of) Haerim Chung(Severance Hospital, Yonsei University College of Medicine, Korea, Republic of) Yuri Kim (YonseiUniversity College of Medicine, Korea, Republic of) Soo Jeong Kim (Yonsei University, College ofMedicine, Korea, Republic of) Jin Seok Kim (Yonsei University College of Medicine, Korea, Republicof) June-Won Cheong (Yonsei University College of Medicine, Korea, Republic of) Min Goo Lee (YonseiUniversity College of Medicine, Korea, Republic of) Hoyoung Lee (Graduate School of Medical Scienceand Engineering, Korea Advanced Institute of Science and Technology, Korea, Republic of) Su-HyungPark (Korea Advanced Institute of Science and Technology, Korea, Republic of) Eui-Cheol Shin(Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science andTechnology, Korea, Republic of) Saeam Shin (Yonsei University College of Medicine, Korea, Republicof) Sun Och Yoon (Yonsei University College of Medicine, Korea, Republic of) Il-Kyu Choi (DGIST,Korea, Republic of) Jeong Seok Lee (Korea Advanced Institute of Science and Technology, Korea,Republic of) Hyunsoo Cho (Yonsei University College of Medicine, Korea, Republic of)Abstract:Emerging evidence indicates that CD4+ T cells contribute to antitumor immunity beyond theirtraditional roles as helpers or regulators. However, the specific subset of CD4+ T cells mediatingbeneficial outcomes in patients with multiple myeloma remains unclear. Here, we performed singlecell RNA sequencing and T cell receptor sequencing on CD4+ T cells sorted from the bone marrow ofp