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(Ebook) Mechanisms of Drug Resistance in Epilepsy Lessons from Oncology 1st Edition by Novartis Foundation ISBN 047084146X 9780470841464

  • SKU: EBN-2110788
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Authors:Novartis Foundation
Pages:255 pages.
Year:2002
Editon:1
Publisher:Wiley
Language:english
File Size:79.84 MB
Format:pdf
ISBNS:047084146X
Categories: Ebooks

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(Ebook) Mechanisms of Drug Resistance in Epilepsy Lessons from Oncology 1st Edition by Novartis Foundation ISBN 047084146X 9780470841464

(Ebook) Mechanisms of Drug Resistance in Epilepsy Lessons from Oncology 1st Edition by Novartis Foundation - Ebook PDF Instant Download/Delivery: 047084146X, 9780470841464
Full download (Ebook) Mechanisms of Drug Resistance in Epilepsy Lessons from Oncology 1st Edition after payment

Product details:

ISBN 10: 047084146X 
ISBN 13: 9780470841464
Author: Novartis Foundation

The object of this book is to gather together workers in the fields of epilepsy, those concerned with the basic science of resistance and the blood-brain barrier, and those with clinical experience of drug resistance in cancer, with a view to stimulating further work on drug resistance in epilepsy. Whilst resistance in cancer has been extensively studied, and trials of reversal of resistance have been undertaken, with some success, resistance in epilepsy has only just begun to be addressed.

(Ebook) Mechanisms of Drug Resistance in Epilepsy Lessons from Oncology 1st Table of contents:

  1. Chair's Introduction

  2. The Problem of the Drug-Resistant Epilepsies

  3. Drug Resistance Molecules: Lessons from Oncology

  4. Drug Resistance in Epilepsy: The Role of the Blood-Brain Barrier

  5. P-Glycoprotein and the Mechanism of Multidrug Resistance

  6. Drug Resistance Caused by Multidrug Resistance-Associated Proteins

  7. Reversal of Multidrug Resistance: Lessons from Clinical Oncology

  8. Clinical Development of P-Glycoprotein Modulators in Oncology

  9. Gene Expression Profiling of Epothilone A-Resistant Cells

  10. Imaging of P-Glycoprotein Function In Vivo with PET

  11. Animal Models of Drug-Resistant Epilepsy

  12. Drug Resistance in Epilepsy: Human Epilepsy

  13. Cellular Mechanisms of Pharmacoresistance in Slices from Epilepsy Surgery

  14. Functional Polymorphisms of the Human Multidrug Resistance (MDR1) Gene: Correlation with P-Glycoprotein Expression and Activity In Vivo

  15. OC144-093: A Novel P-Glycoprotein Inhibitor for the Enhancement of Anti-Epileptic Therapy

  16. Closing Remarks

  17. Index of Contributors

  18. Subject Index

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Tags: Novartis Foundation, Mechanisms, Drug

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