Kidney immunology from pathophysiology to clinical translation by Christian Kurts & Sibylle Vietinghoff & Christian F. Krebs & Ulf Panzer instant download

Kidney immunology from pathophysiology to clinical translation by Christian Kurts & Sibylle Vietinghoff & Christian F. Krebs & Ulf Panzer instant download

Kidney diseases are widespread and represent a considerable medical, Introductionsocial and economic burden. However, there has been marked progress Kidney structure and functionin understanding the immunological aspects of kidney disease. Immune mechanisms in This includes the identifcation of distinct intrarenal immunological glomerulonephritisniches and characterization of kidney disease endotypes according Immune mechanisms in to the underlying molecular immunopathology, as well as a better tubulointerstitial kidney diseaseunderstanding of the pathological roles for T cells, mononuclear Infectious kidney diseasesphagocytes and B cells and the renal elements they target. These insights have improved the diagnosis of kidney disease. Here, we discuss new Immune crosstalk between the kidney and other organsdevelopments in our understanding of kidney immunology, focusing on immune mechanisms of disease and their translational implications Perspectivesfor the diagnosis and treatment of kidney disease. We also describe the immune-mediated crosstalk between the kidney and other organs that infuences kidney disease and extrarenal infammation.