(Ebook) Insulin Resistance: Insulin Action and its Disturbances in Disease by Sudhesh Kumar, Stephen O'Rahilly ISBN 9780470011263, 9780470850084, 0470011262, 0470850086

(Ebook) Insulin Resistance: Insulin Action and its Disturbances in Disease by Sudhesh Kumar, Stephen O'Rahilly ISBN 9780470011263, 9780470850084, 0470011262, 0470850086

Diabetes is now one of the major causes of morbidity worldwide. In many cases, the onset of diabetes is progressive, developing via a condition of insulin resistance. This book considers the development of this condition, its consequences and clinical and therapeutic aspects.The book reviews the normal biology of insulin action on glucose, lipids and proteins. It considers the pathological basis for insulin resistance in animal models and humans, and discusses the influence of heredity, dietary factors and exercise. Clinical consequences including dyslipidaemia, hypertension and polycystic ovary syndrome, and therapeutic strategies for treatment are also examined.* Provides an expert review of the phenomenon of insulin resistance* Brings together a host of recent research for the first time* Written by leading experts in biological and clinical research