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Status:
Available4.4
16 reviewsISBN 10: 390639025X
ISBN 13: 9783906390253
Author: Bernard Testa, Joachim M Mayer
Many drugs and other xenobiotics (e.g., preservatives, insecticides, and plastifiers) contain hydrolyzable moieties such as ester or amide groups. In biological media, such foreign compounds are, therefore, important substrates for hydrolytic reactions catalyzed by hydrolases or proceeding non-enzymatically.
Despite their significance, until now, no book has been dedicated to hydrolysis and hydrolases in the metabolism of drugs and other xenobiotics. This work fills a gap in the literature and reviews metabolic reactions of hydrolysis and hydarion from the point of views of enzymes, substrates, and reactions.
hydrolysis in drug and prodrug metabolism
hydrolysis in drug and prodrug metabolism chemistry biochemistry and enzymology
drug metabolism hydrolysis
hydrolysis drug metabolism
hydrolysis in metabolism
Tags: Bernard Testa, Joachim M Mayer, Hydrolysis, Drug