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17 reviews(Ebook) Human Embryonic Stem Cells 1st Edition by Jon Odorico, Roger Pedersen, Su Chun Zhang - Ebook PDF Instant Download/Delivery: 9780203487341 ,0203487346
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Product details:
ISBN 10: 0203487346
ISBN 13: 9780203487341
Author: Jon Odorico, Roger Pedersen, Su Chun Zhang
(Ebook) Human Embryonic Stem Cells 1st Edition Table of contents:
1. Biology of embryonic stem cells
Introduction
Derivation and definition of mouse ES cells
The molecular basis of ES cell pluripotency
Differentiation of ES cells
Applications of ES cell technology
2. Characteristics of human embryonic stem cells, embryonal carcinoma cells and embryonic germ cells
Introduction
Sources of stem cells
Embryoid body-derived (EBD) cells
Markers of pluripotency
3. Adult stem cell plasticity
Introduction
Stem cells – definition
Adult stem cells
Adult stem cells – plasticity
Plasticity of hematopoietic bone marrow cells
Plasticity of mesenchymal stem cells
Mulitpotent adult progenitor cells
Plasticity of skeletal muscle cells
Plasticity of neural cells
Mechanisms of plasticity
Potential uses of adult stem cells
4. Human and murine embryonic stem cell lines: windows to early mammalian development
Introduction
Derivation, growth and morphology of murine and human ES cells
ES cells as an in vitro model of early mammalian development
ES cells: a renewable source of functional cells
Summary
5. Human mesenchymal stem cells and multilineage differentiation to mesoderm lineages
Human mesenchymal stem cells (hMSCs) in culture
Differentiation towards mesenchymal lineages: lessons from hMSCs
Synergy of hMSC and hES research
Conclusion
6. Trophoblast differentiation from embryonic stem cells
Origin and development of the placenta: introduction
Bridging the mouse-human gap in placental biology
Summary and future prospects
7. Current and future prospects for hematopoiesis studies using human embryonic stem cells
Introduction
Lessons from mouse ES cell-based hematopoiesis
Hematopoiesis from human ES cells: studies to date
Hematopoiesis from human ES cells: the next stage
Human embryonic stem cells, preimplantation genetic diagnosis, and hematopoiesis
Summary
Color plates can be found between p. 136 and p. 137.
8. Derivation of endothelial cells from human embryonic stem cells
Introduction
Development of endothelial cell progenitors
Isolation of endothelial cells and their progenitors
Characterization techniques for isolated endothelial cells
Therapeutic applications of endothelial cell progenitors
Challenges today and hopes for tomorrow
9. Neural specification from human embryonic stem cells
Introduction
Neural induction in vertebrates
Embryonic stem cells as a window to mammalian neural development
Neural differentiation from mouse ES cells
Neural differentiation from human ES cells
Outstanding questions
10. Modeling islet development through embryonic stem cell differentiation
Introduction
Development of the pancreas and islets of Langerhans in vertebrates
Islet differentiation from embryonic stem cells
Recapitulating developmental pathways of islet differentiation in ES cells
Remaining questions
Summary
11. Cardiomyocyte differentiation in human embryonic stem cell progeny
Introduction
Early signals in cardiac development
In vitro differentiation of mouse and human ES cells to cardiomyocytes
Prospects for myocardial regeneration
Summary
12. Genetic engineering of human embryonic stem cells
Introduction
Methods for introduction of DNA into human ES cells
Alteration of gene expression in human ES cells
The potential clinical applications of genetically modified human ES cells
Conclusions
13. ES cells for transplantation: coping with immunity
Introduction
Immune profile
Strategies for matching donor and recipient
Strategies for preventing allograft rejection
Concluding comments
14. Clinical applications for human ES cells
Introduction
Goals for bringing hES cell-based therapy to clinical practice
Tissue engineering with hES cells
Cell-based therapy for delivery of bioactive molecules
Somatic cell nuclear transfer and hES cells
Progress and promise in disease-specific cell therapies
Future
15. Production of human embryonic stem cell-derived cellular product for therapeutic use
Introduction
Required properties for a hESC-based cell therapy
Qualification of hESCs and raw materials
Cell production
Conclusions
16. Ethical and policy considerations in embryonic stem cell research
Federal regulation of embryo research
The origins of the de facto ban on federal funding for embryo research
Origins of the de jure ban on federal funding for embryo research
Origins of the decision to permit general federal funding of research on embryonic stem cell lines
The decision to narrow the eligibility requirements for federal funding of research with human embryonic stem cells
The intersection of embryo research funding and the abortion debate
Summary
17. Legal framework pertaining to research creating or using human embryonic stem cells
Introduction
Federal statute
Patent rights, licensing programs and agreements
State regulation of research involving embryos
International legal framework
Summary
18. Genomic approaches to stem cell biology
Introduction
Large-scale isolation of new genes from early embryos and stem cells
Methods for gene expression profiling
Data analysis and bioinformatics
Expression profiling of stem cells
Follow-up study of cDNA microarrays
cDNA microarray analysis of cloned animals
Large-scale functional studies of genes
Future perspectives
19. Proteomics and embryonic stem cells
Introduction
Making elephants fly
Mass spectrometry instrumentation
Protein and peptide chemistry
Better proteomics through chemistry
Baby steps
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Tags: Jon Odorico, Roger Pedersen, Su Chun Zhang, Human Embryonic, Stem Cells
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