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Status:
Available4.3
22 reviewsISBN 10: 0896036731
ISBN 13: 9780896036734
Author: V. Craig Jordan, B.J.A. Furr
In Hormone Therapy in Breast and Prostate Cancer, many of today's leading researchers and clinicians describe the principles underlying targeted hormonal treatments, assess the actions of new and established agents, and illustrate the new applications of hormonal chemoprevention for breast cancer. Topics range from preclinical and clinical antiestrogens to the inhibition of estrogen synthesis and the effects of androgen withdrawal. A wide variety of proven and new agents are discussed-antiestrogens, including aromatase inhibitors (anastrozole, letrozole, and others), SERMs (tamoxifen, raloxifene, and others), and such antiandrogenic strategies as goserelin and bicalutamide.
1. An Introduction to the Regulation of Sex Steroids for the Treatment of Cancer
2. Preclinical Antiestrogens
3. Antiestrogens and the Cell Cycle
4. Drug Resistance to Antiestrogens
5. Mechanisms of Liver Carcinogenesis by Antiestrogens
6. The Effects of Triphenylethylene Antiestrogens on Parameters of Multistage Hepatocarcinogenesis in the Rat
7. Preclinical Studies of Raloxifene and Related Compounds
8. Pure Antiestrogens
9. Antiestrogens: Clinical
10. Tamoxifen for the Treatment of Breast Cancer
11. Clinical Utility of New Antiestrogens
12. Breast Cancer Prevention with Antiestrogens
13. Inhibition of Estrogen Synthesis
14. Aromatase Inhibitors
15. Clinical Utility of Aromatase Inhibitors
16. LH-RH Agonists for the Treatment of Breast Cancer
17. Androgens and Androgen Withdrawal
18. Molecular Action of Androgens
19. Steroidal Antiandrogens
20. Nonsteroidal Antiandrogens
21. LH-RH Agonist Role in Prostate Cancer Management
22. Perspective on Progress
23. Recent Progress in Breast Cancer Research
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Tags: Craig Jordan, Furr, Hormone therapy, prostate cancer
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