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13 reviewsISBN-10 : 0824726472
ISBN-13 : 9780824726478
Author: Dilip M. Parikh
The Third Edition presents all pharmaceutical industry personnel and those in academia with critical updates on the recent advances in granulation technology and changes in FDA regulatory guidelines. Addressing precisely how these recent innovations and revisions affect unit operation of particle generation and granulation, this text assists the reader in selecting the ideal technology for his/her company’s particular drug delivery system. This knowledge helps ensure that regulatory guidelines are followed and met in a cost-effective manner.
1. Introduction
2. Theory of Granulation: An Engineering Perspective
3. Drug Substance and Excipient Characterization
4. Binders and Solvents
5. Spray Drying and Pharmaceutical Applications
6. Roller Compaction Technology
7. High-Shear Granulation
8. Low-Shear Granulation
9. Batch Fluid Bed Granulation
10. Single-Pot Processing
11. Extrusion/Spheronization as a Granulation Technique
12. Effervescent Granulation
13. Melt Granulation and Pelletization
14. Rapid Release Granulation
15. Continuous Granulation Technologies
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Tags: Handbook, Pharmaceutical, Granulation, Technology, Dilip Parikh