Most ebook files are in PDF format, so you can easily read them using various software such as Foxit Reader or directly on the Google Chrome browser.
Some ebook files are released by publishers in other formats such as .awz, .mobi, .epub, .fb2, etc. You may need to install specific software to read these formats on mobile/PC, such as Calibre.
Please read the tutorial at this link. https://ebooknice.com/page/post?id=faq
We offer FREE conversion to the popular formats you request; however, this may take some time. Therefore, right after payment, please email us, and we will try to provide the service as quickly as possible.
For some exceptional file formats or broken links (if any), please refrain from opening any disputes. Instead, email us first, and we will try to assist within a maximum of 6 hours.
EbookNice Team
Status:
Available4.9
7 reviewsSelective inheritance of sub-cellular components has emerged as a mechanismguiding stem cell fate after asymmetric cell divisions. Peroxisomes play acrucial role in multiple metabolic processes such as fatty acid metabolism andreactive oxygen species detoxification, but the apportioning of peroxisomesduring stem cell division remains understudied. Here, we develop a mousemodel and labeling technique to follow the dynamics of distinct peroxisomeage-classes, and find that old peroxisomes are inherited by the daughter cellretaining full stem cell potency in mammary and epidermal stem cell divisions.Old peroxisomes carry Glucose-6-phosphate-dehydrogenase, whose specificlocation on the peroxisomal membrane promotes stem cell function byfacilitating peroxisomal ether lipid synthesis. Our study demonstrates ageselective apportioning of peroxisomes in vivo, and unveils how functionalheterogeneity of peroxisomes is utilized by asymmetrically dividing cells tometabolically divert the fate of the two daughter cells.