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(Ebook) Fluoropyrimidines in Cancer Therapy by G. J. Peters PhD (auth.), Youcef M. Rustum (eds.) ISBN 9781592593378, 9781617372742, 1592593372, 1617372749

  • SKU: EBN-11851326
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Authors:G. J. Peters PhD (auth.), Youcef M. Rustum (eds.)
Pages:326 pages.
Year:2003
Editon:1
Publisher:Humana Press
Language:english
File Size:10.77 MB
Format:pdf
ISBNS:9781592593378, 9781617372742, 1592593372, 1617372749
Categories: Ebooks

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(Ebook) Fluoropyrimidines in Cancer Therapy by G. J. Peters PhD (auth.), Youcef M. Rustum (eds.) ISBN 9781592593378, 9781617372742, 1592593372, 1617372749

Leading cancer researchers update and review the mechanisms of action and the therapeutic selectivity and efficacy of 5-FU with and without leucovorin and its prodrugs in the treatment of colorectal cancer. Among the combination agents considered are UFT/LV, 5-FU/EU, capecitabine (Xeloda), S-1, and a variety of thymidylate synthase inhibitors. The authors discuss the potential advantages and disadvantages of these varied drugs and their mode of administration. Based on historical results with these agents when used alone, they also present a rationale for their results when used in combination with other agents.
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