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17 reviewsBread wheat (Triticum aestivum) has undergone a complex evolutionary history Highlights shaped by polyploidization, domestication, and adaptation. Recent advances Epigenomic changes stabilize genome in multiomics approaches have shed light on the role of epigenetic mechanisms, shock after polyploidization, aiding the establishment of polyploidy wheat. including DNA methylation, histone modification, chromatin accessibility, and Moreover, the resulting epigenomic dinoncoding RNAs, in regulating gene expression throughout these processes. versity promotes subgenome-specific Epigenomic reprogramming contributes to genome stability and subgenome difdifferentiation. ferentiation and modulates key agronomic traits by influencing flowering time, During wheat adaptation and developenvironmental responses, and developmental programs. This review synthement, epigenetic regulators can be insizes current insights into epigenetic regulation of wheat speciation, adaptation, duced by environmental or external and development, highlighting their potential applications in crop improvement. cues to reshape the epigenome, or they A deeper understanding of these mechanisms will facilitate targeted breeding can be recruited by specific transcription factors to alter the chromatin state of tarstrategies leveraging epigenetic variations to enhance wheat resilience and proget genes .ductivity in the face of changing environments.