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0 reviewsDynamic profiling of BMSC-dECM reveals accumulation of core matrisome proteins suppresses osteogenic differentiation and bone regenerationMei Li1, Weilai Zhu2, Mingyu Hu2, Xufeng Mao3, Bowen Weng2, Jing Peng2, Shuishui Yin2, Haijiao Mao3, Jiyuan Zhao2, *1 Key Laboratory of Precision Medicine for Atherosclerotic Diseases of Zhejiang Province, the First Affiliated Hospital of Ningbo University, Ningbo University, Ningbo, Zhejiang, People's Republic of China.2 Zhejiang Key Laboratory of Pathophysiology, School of Medicine, Ningbo University, Ningbo, Zhejiang, People's Republic of China.3 Department of Orthopaedic Surgery, the First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, People's Republic of China.* Corresponding author:Jiyuan Zhao, Address: School of Medicine, Ningbo University, 818 Fenghua Road, Ningbo, Zhejiang 315211, China. Phone: +86-574-8760-9596. E-mail address: [email protected] Email [email protected] (Mei Li); [email protected] (Weilai Zhu); [email protected] (Mingyu Hu); [email protected] (Xufeng Mao); [email protected] (Bowen Weng); [email protected] (Jing Peng); [email protected] (Shuishui Yin); [email protected] (Haijiao Mao)Acknowledgements This work was supported by Natural Science Foundation of Zhejiang Province (LY22H060005, LY24H160001), Ningbo major science and technology project (2024Z205, 2022Z133). The graphic abstract was created with BioRender.com.Credit author statementMei Li, Weilai Zhu, Mingyu Hu, Xufeng Mao, Bowen Weng, Jing Peng and Shuishui Yin performed investigation. Mei Li, Weilai Zhu and Mingyu Hu performed 1