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7 reviews(Ebook) Drug Nucleic Acid Interactions 1st Edition by Jonathan B Chaires, Michael J Waring - Ebook PDF Instant Download/Delivery: 0121822419 ,9780121822415
Full download (Ebook) Drug Nucleic Acid Interactions 1st Edition after payment
Product details:
ISBN 10: 0121822419
ISBN 13: 9780121822415
Author: Jonathan B Chaires, Michael J Waring
(Ebook) Drug Nucleic Acid Interactions 1st Edition Table of contents:
Section I: Biophysical Approaches
Chapter 1. Analysis and Interpretation of Ligand–DNA Binding Isotherms
Chapter 2. Surface Plasmon Resonance Biosensor Analysis of RNA–Small Molecule Interactions
Chapter 3. Simultaneous Measurement of Binding Constants and Unwinding Angles by Gel Electrophoresis
Chapter 4. Linear and Circular Dichroism of Drug–Nucleic Acid Complexes
Chapter 5. Rapid Screening of Structurally Selective Ligand Binding to Nucleic Acids
Chapter 6. Calorimetric Techniques in the Study of High-Order DNA–Drug Interactions
Chapter 7. Volume Changes Accompanying Interaction of Ligands with Nucleic Acids
Chapter 8. Calculating Sequence-Dependent Melting Stability of Duplex DNA Oligomers and Multiplex Se
Chapter 9. Thermal Denaturation as Tool to Study DNA–Ligand Interactions
Chapter 10. Kinetics of Binding of Hoechst Dyes to DNA Studied by Stopped-Flow Fluorescence Techniqu
Chapter 11. Scanning Force Microscopy of Nucleic Acid Complexes
Chapter 12. Nuclear Magnetic Resonance Studies of Drug–DNA Complexes in Solution
Chapter 13. X-Ray Crystallography of DNA–Drug Complexes
Chapter 14. Molecular Modeling of Drug–DNA Complexes: An Update
Section II: Chemical and Molecular Biological Approaches
Chapter 15. Peptide Nucleic Acid Targeting of Double-Stranded DNA
Chapter 16. Drug Interaction with Triple-Helical Nucleic Acids
Chapter 17. Measurement of Covalent Drug–DNA Interactions at the Nucleotide Level in Cells at Phar
Chapter 18. Targeting DNA through Covalent Interactions of Reversible Binding Drugs
Chapter 19. Chemical Cross-Linking of Drugs to DNA
Chapter 20. High-Resolution Footprinting Studies of Drug–DNA Complexes Using Chemical and Enzymati
Chapter 21. Drug–RNA Footprinting
Chapter 22. Footprinting Methods for Analysis of Pyrrole–Imidazole Polyamide/DNA Complexes
Chapter 23. High-Resolution Transcription Assay for Probing Drug–DNA Interactions at Individual Dr
Chapter 24. Use of DNA Molecules Substituted with Unnatural Nucleotides to Probe Speci.c Drug–DNA
Chapter 25. Drug Interactions with Nucleosomes and Chromatin
Chapter 26. Locating Cobalt-Binding Sites on DNA Using Restriction Endonucleases
Chapter 27 Exploiting Anthracycline Scaffold for Designing DNA-Targeting Agents
Chapter 28. Design, Synthesis, and Characterization of Polyintercalating Ligands
Section III: Enzymology and Biological Approaches
Chapter 29. Targeting Telomeres and Telomerase
Chapter 30. Rapid, High-Throughput Engineering of Sequence-Specific Zinc Finger DNA-Binding Proteins
Chapter 31. DNA Relaxation and Cleavage Assays to Study Topoisomerase I Inhibitors
Chapter 32. In Vitro Human Immunodeficiency Virus Type 1 Integrase Assays
Chapter 33. Use of Xenopus Egg Extracts to Study Effects of DNA-Binding Drugs on Chromatin Assembly,
Author Index
Subject Index
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Tags: Jonathan B Chaires, Michael J Waring, Drug Nucleic, Acid Interactions
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