(Ebook) COVID Reference ENG 2021.6 (13 January 2021) by Bernd Sebastian Kamps, Christian Hoffmann ISBN 9783942687539, 3942687534

(Ebook) COVID Reference ENG 2021.6 (13 January 2021) by Bernd Sebastian Kamps, Christian Hoffmann ISBN 9783942687539, 3942687534

0. Top 10 171. Epidemiology 19Hotspots of SARS-CoV-2 Transmission 23Special Aspects of the Pandemic 38The SARS-CoV-2 pandemic: Past and Future 47The 2020 Lockdowns 48Outlook 52References 542. Transmission 69Summary 69Introduction 70The Virus 70Person-to-person transmission 72Routes of Transmission 73Transmission Event 82End of Quarantine 95Prevention 96Outlook 98References 993. Prevention 117Introduction 117Containment or mitigation of COVID-19? 134Conclusion 135References 1364. Virology 153Introduction 153References 15414 | CovidReference.comKamps – Hoffmann5. Vaccines 171Summary 171Approved SARS-CoV-2 vaccines – An overview 171Vaccines 179Vaccine platforms 184Vaccine candidates in Phase III Trials 186Immunization fundamentals 192Questions for the Future 196Outlook 199References 2016. Diagnostic Tests and Procedures 213Diagnosis 213Radiology 231References 2347. Clinical Presentation 243Incubation period 243Asymptomatic cases 244Symptoms 246Laboratory findings 257Clinical classification 261Outcome 262Reactivations, reinfections 276Long-term sequelae/Long COVID-19 277Outlook 279References 2798. Treatment 2971. Inhibitors of the viral RNA synthesis 2992. Various antiviral agents 3063. Monoclonal Antibodies and Convalescent Plasma 3094. Immunomodulators 315Other treatments for COVID-19 (with unknown or unprovenmechanisms of action) 323| 15Outlook and Recommendations 326References 3279. Severe COVID-19 337Definition and classification 337Features, course and outcome 337Spotlight: The situation in a German COVID-19 hospital 339Special situations in severe COVID-19 341References 34310. Comorbidities 347Hypertension and cardiovascular comorbidities 348Diabetes mellitus 354COPD and smoking 356HIV infection 357Immunosuppression (other than HIV) 361Cancer 363Transplantation 365Other comorbidities 36711. Pediatrics 369SARS-CoV-2 infection in children 369Epidemiology of COVID-19 in children 370Natural course and risk factors for complications 371Pathophysiology and immunopathology 372Transmission 374Diagnosis and classification 376Management 383References 38912. The First Eight Months 397Dezember - March 397April 413May 422June 428July 439