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(Ebook) Chromosomal Instability and Aging Basic Science and Clinical Implications 1st Edition by Fuki Hisama, Sherman M Weissman, George M Martin ISBN 9780824708566 0824708563

  • SKU: EBN-1783236
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Authors:Fuki Hisama, Sherman M. Weissman, George M. Martin
Pages:600 pages.
Year:2003
Editon:1
Publisher:CRC Press
Language:english
File Size:3.86 MB
Format:pdf
ISBNS:9780824708566, 9780824747305, 0824708563, 0824747305
Categories: Ebooks

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(Ebook) Chromosomal Instability and Aging Basic Science and Clinical Implications 1st Edition by Fuki Hisama, Sherman M Weissman, George M Martin ISBN 9780824708566 0824708563

(Ebook) Chromosomal Instability and Aging Basic Science and Clinical Implications 1st Edition by Fuki Hisama, Sherman M Weissman, George M Martin - Ebook PDF Instant Download/Delivery: 9780824708566 ,0824708563
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Product details:

ISBN 10: 0824708563
ISBN 13: 9780824708566
Author: Fuki Hisama, Sherman M Weissman, George M Martin

This text examines the relationship between DNA damage and repair, cellular senescence, genomic instability, and aging. The authors provide in-depth discussions of various types of DNA damage, the DNA repair network, and cellular responses to genetic damage to assess their impact on the modulation of aging processes and age-related diseases, includ
 

(Ebook) Chromosomal Instability and Aging Basic Science and Clinical Implications 1st Edition Table of contents:

1 Introduction

2 Overview of Chromosomal Instability and Aging Mechanisms

3 Cellular Senescence

4 Telomeric Shortening and Replicative Aging

5 Telomeric Regulation in Eukaryotic Cells

6 Role of Ku at the Telomere

7 Chromosomal Instability in Normative Aging

8 Chromatin, Aging, and Cellular Senescence

9 Werner Syndrome

10 Bloom Syndrome: Genetic, Cellular, and Molecular Features asCompared to Werner Syndrome

11 Molecular Biology ofRothmund-Thomson Syndrome

12 Hutchinson-Gilford Progeria Syndrome

13 Ataxia-Telangiectasia

14 Nijmegen Breakage Syndrome

15 Dyskeratosis Congenita

16 Genetic Instability and FanconiAnemia

17 Xeroderma Pigmentosum

18 Down Syndrome

19 Genomic Instability andYeast Aging

20 Genetics of Aging in the Nematode

21 Aging, Somatic Maintenance, and Genomic Stability in Drosophilamelanogaster

22 Telomerase-Deficient Mouse Model

23 Animal Models of Oxidative Stress and Aging

24 Conclusions and Future Directions

Index

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Tags: Fuki Hisama, Sherman M Weissman, George M Martin, Chromosomal Instability, Aging Basic Science

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