(Ebook) Chemical Biology: Approaches to Drug Discovery and Development to Targeting Disease by Natanya Civjan ISBN 9781118101186, 1118101189

(Ebook) Chemical Biology: Approaches to Drug Discovery and Development to Targeting Disease by Natanya Civjan ISBN 9781118101186, 1118101189

An authoritative look at the application of chemical biology in drug discovery and developmentBased on the award-winning Wiley Encyclopedia of Chemical Biology published in 2008, this book explores the role of chemical biology in drug discovery and development. The first part of the book reviews key principles and techniques used in the design and evaluation of drug candidates. The second part elucidates biological mechanisms of certain diseases, illuminating approaches to investigate and target these diseases.Comprising carefully selected reprints from the Encyclopedia as well as new contributions from leading scholars in the field, this book provides researchers in academia and industry with important information to aid in the development of novel agents to treat disease. Self-contained articles cover a variety of essential topics, including:The design, development, and optimization of drug candidatesThe pharmacokinetics and properties of drugsDrug transport and deliveryNatural products and natural product models as pharmaceuticalsBiological mechanisms underlying health and diseaseTreatment strategies for a range of diseases, from HIV to schizophreniaChemical Biology is a top-notch guide and reference for anyone working in the areas of drug discovery and development, including researchers in chemical biology and other fields such as biochemistry, medicine, and pharmaceutical sciences