(Ebook) Cellular Mechanisms of Alzheimer s Disease Neurodegenerative Diseases 2006 1st Edition by C Haass, G Multhaup ISBN 9783805581837 3805581831

(Ebook) Cellular Mechanisms of Alzheimer s Disease Neurodegenerative Diseases 2006 1st Edition by C Haass, G Multhaup ISBN 9783805581837 3805581831

(Ebook) Cellular Mechanisms of Alzheimer s Disease Neurodegenerative Diseases 2006 1st Edition by C Haass, G Multhaup - Ebook PDF Instant Download/Delivery: 9783805581837 ,3805581831
Full download (Ebook) Cellular Mechanisms of Alzheimer s Disease Neurodegenerative Diseases 2006 1st Edition after payment

Product details:

ISBN 10: 3805581831
ISBN 13: 9783805581837
Author: C Haass, G Multhaup

(Ebook) Cellular Mechanisms of Alzheimer s Disease Neurodegenerative Diseases 2006 1st Edition Table of contents:

Six Years of Collaborative Alzheimer’s Disease Research in Germany
The Microtubule-Associated Protein Tau
Primary Structure of Tau and Prediction of Folding
Global Features of Unfolded Proteins
Long-Range Structure in Tau
(Un)folding and Aggregation
Conclusions
References
Introduction
Materials and Methods
MARK
MARKK
Outlook: Modes of MARK Regulation
References
Subcellular Trafficking of APP/APLPs
Pathogenic Role of the APP Gene Family in Axonal Transport
References
Introduction
Presenilin Function in C. elegans
Suppressors and Enhancers of Presenilin in C. elegans
References
Abstract
References
Introduction
APP/APLP Loss of Function Studies
Roles of APP/APLP Proteins in the Formation of Neuromuscular Synapses and in Cortical Development
Acknowledgement
References
Trafficking and Proteolytic Processing of APP
Role of Glycosphingolipids in the Subcellular Transport of APP and the Generation of Abeta
Role of BACE1 and BACE2 in APP Processing
Role of GGA Proteins in the Proteolytic Processing of betaAPP
References
Introduction
Identification of ADAM10 as an alpha-Secretase
Transcriptional Regulation of the Human alpha-Secretase ADAM10 Gene
Activation of alpha-Secretase via G Protein-Coupled Receptors
Concluding Remarks
References
Proteolytic Processing of APP
Expression Cloning Screen for Modifiers of APP Shedding
Specificity of Identified cDNAs for APP Shedding
Control of APP Shedding by Modulators of General Endocytosis
APLP1 Modulates APP Shedding
Conclusion
References
Abstract
References
Introduction
Identification of gamma-Secretase
Localization of gamma-Secretase and Its Cellular Site(s) of Activity
Assembly of the gamma-Secretase Complex
Acknowledgments
References
Introduction
SPP-Like Proteins
Nicalin (Nicastrin-Like Protein)
References
BACE Inhibitors
Gamma-Secretase Inhibitors
Outlook
References
Introduction: Abeta42 as a Therapeutic Target in Alzheimer’s Disease
Gamma-Secretase Inhibition versus gamma-Secretase Modulations
Abeta42-Lowering Compounds: In vitro Studies and Mechanism of Action
Preclinical in vivo Studies and Clinical Trials with Abeta42-Lowering Compounds
Acknowledgement
References
APP Processing
Lipids – Risk Factor for AD
The Role of APP and PSs in vivo
Statins and Abeta-Mediated Cholesterol Downregulation
Acknowledgement
References
Subject Index

People also search for (Ebook) Cellular Mechanisms of Alzheimer s Disease Neurodegenerative Diseases 2006 1st Edition:

    
alzheimer's disease organelle affected
    
alzheimer's disease organelle
    
cellular mechanisms of diabetes
    
explain the pathophysiology of alzheimer’s disease
    
explain the pathophysiology of alzheimer's disease

Tags: C Haass, G Multhaup, Cellular Mechanisms, Alzheimer s Disease