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34 reviewsISBN 10: 0815344414
ISBN 13: 978-0815344414
Author: Raif Geha, Luigi Notarangelo
Case Studies in Immunology, Sixth Edition, presents major topics of immunology through a selection of clinical cases that reinforce and extend the basic science. The case histories illustrate essential points about the mechanisms of immunity and describe immunological problems seen in the clinic. This new edition vividly illustrates the importance of an understanding of immunology in diagnosis and therapy. Case Studies in Immunology highlights major common disorders of immunity, including hypersensitivity types I-IV, immune deficiencies, and autoimmune disorders. Each case history is preceded by basic scientific facts essential to understanding the immunology behind the specific disorders. An end-of-case summary, questions, and discussion points conclude each case.
Case Studies in Immunology can be used as a stand-alone book, or as a clinical companion alongside Janeway’s Immunobiology, Eighth Edition. A marginal icon in Janeway’s Immunobiology provides the reader with a link to the relevant Case Study, where the science is applied in a clinical setting.
The book includes a total of 53 cases. The Sixth Edition is extensively revised and updated and includes ten new cases:
DiGeorge Syndrome
Hemophagocytic Lymphohistiocytosis
Chediak-Higashi Syndrome
Hyper IgE Syndrome
Ataxia Telangiectasia
Warts, Hypogammaglobulinemia, Infections, and Myelokathexis (WHIM) Syndrome
Severe Congenital Neutropenia
Recurrent Herpes Simplex Encephalitis
Systemic Onset Juvenile Idiopathic Arthritis
Crohn’s Disease
Case 1
Congenital Asplenia
Case 2
Chronic Granulomatous Disease
Case 3
Leukocyte Adhesion Deficiency
Case 4
Hereditary Angioneurotic Edema
Case 5
Factor I Deficiency
Case 6
Deficiency of the C8 Complement Component
Case 7
Hereditary Periodic Fever Syndromes
Case 8
Interleukin 1 Receptor-associated Kinase 4 Deficiency
Case 9
X-linked Hypohydrotic Ectodermal Dysplasia and Immunodeficiency
Case 10
X-linked Agammaglobulinemia
Case 11
X-linked Hyper IgM Syndrome
Case 12
Activation-induced Cytidine Deaminase (AID) Deficiency
Case 13
Common Variable Immunodeficiency
Case 14
X-linked Severe Combined Immunodeficiency
Case 15
Adenosine Deaminase Deficiency
Case 16
Omen Syndrome
Case 17
MHC Class | Deficiency
Case 18
MHC Class II Deficiency
Case 19
Multiple Myeloma
Case 20
T-Cell Lymphoma
Case 21
Interferon-γ Receptor Deficiency
Case 22
Wiskott-Aldrich Syndrome
Case 23
X-linked Lymphoproliferative Syndrome
Case 24
Autoimmune Lymphoproliferative Syndrome (ALPS)
Case 25
Immune Dysregulation, Polyendocrinopathy, Enteropathy X-linked Disease
Case 26
Toxic Shock Syndrome
Case 27
Acute Infectious Mononucleosis
Case 28
Mixed Essential Cryoglobulinemia
Case 29
Rheumatic Fever
Case 30
Lepromatous Leprosy
Case 31
Acquired Immune Deficiency Syndrome (AIDS)
Case 32
Acute Systemic Anaphylaxis
Case 33
Allergic Asthma
Case 34
Atopic Dermatitis
Case 35
Drug-Induced Serum Sickness
Case 36
Celiac Disease
Case 37
Contact Sensitivity to Poison Ivy
Case 38
Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy
Case 39
Autoimmune Hemolytic Anemia
Case 40
Myasthenia Gravis
Case 41
Pemphigus Vulgaris
Case 42
Rheumatoid Arthritis
Case 43
Systemic Lupus Erythematosus
Case 44
Multiple Sclerosis
Case 45
Hemolytic Disease of the Newborn
Case 46
A Kidney Graft for Complications of Autoimmune Insulin-Dependent Diabetes Mellitus
Case 47
Graft-Versus-Host Disease
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Tags: Raif Geha, Luigi Notarangelo, Case Studies, in Immunology, Clinical Companion