(Ebook) Bioinformatics and Drug Discovery 1st Edition by Eliot Ohlstein, Anthony Johnson, John Elliott, Richard Larson ISBN 978-1592599646 1592599646

(Ebook) Bioinformatics and Drug Discovery 1st Edition by Eliot Ohlstein, Anthony Johnson, John Elliott, Richard Larson ISBN 978-1592599646 1592599646

(Ebook) Bioinformatics and Drug Discovery 1st Edition by Eliot H. Ohlstein, Anthony G. Johnson, John D. Elliott, Richard S. Larson  - Ebook PDF Instant Download/Delivery: 978-1592599646, 1592599646
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Product details: 

ISBN 10:  1592599646

ISBN 13: 978-1592599646

Author: Eliot H. Ohlstein, Anthony G. Johnson, John D. Elliott, Richard S. Larson 

A collection of readily reproducible bioinformatic methods to advance the drug discovery process from gene identification to protein modeling to the identification of specific drug candidates. The authors demonstrate these techniques, including microarray analysis, the analysis of genes as potential drug targets, virtual screening and in silico protein design, and cheminformatics, in a variety of practical situations. Because these technologies are still emergent, each chapter contains an extended introduction that explains the theory and application of the technology and techniques described.

Table of contents: 

PART I. Bioinformatics and Microarray Technologies

1. New Strategies in Drug Discovery

2. Basic Microarray Analysis

3. From Microarray to Biological Networks

4. Microarray Analysis in Drug Discovery and Clinical Applications

5. Ontology-Driven Approaches to Analyzing Data in Functional Genomics

6. Gene Evolution and Drug Discovery

7. Standardization of Microarray and Pharmacogenomics Data

8. Clinical Applications of Bioinformatics, Genomics, and Pharmacogenomics

PART II. Protein-Based and Structural Approaches in Drug Discovery
9. Protein Interactions Probed With Mass Spectrometry
10. Discovering New Drug-Targeting Sites on Flexible Multidomain Protein Kinases
11. Nuclear Magnetic Resonance-Based Screening Methods for Drug Discovery
12. Receptor-Binding Sites
13. In Silico Protein Design

PART III. Computational Tools and Database Applications
14. Chemical Database Preparation for Compound Acquisition or Virtual Screening
15. Bioinformatics Platform Development

Back Matter

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Tags: Eliot Ohlstein, Anthony Johnson, John Elliott, Richard Larson, Bioinformatics and Drug