Alzheimer's disease : cellular and molecular aspects of amyloid [beta], Alzheimer's Disease : Cellular and Molecular Aspects of Amyloid β / elektronisch by Harris, J. Robin (James Robin); Fahrenholz, F. (Falk) instant download

Alzheimer's disease : cellular and molecular aspects of amyloid [beta], Alzheimer's Disease : Cellular and Molecular Aspects of Amyloid β / elektronisch by Harris, J. Robin (James Robin); Fahrenholz, F. (Falk) instant download

1 online resource (xv, 409 pages) :, \"The volume contains a broad range of current information on cellular, biochemical, and structural aspects of amyloid-[beta], of direct relevance to Alzheimer's disease.\"--Jacket, Includes bibliographical references and index, Print version record, The Contribution of Microscopy to the Study of Alzheimer's Disease, Amyloid Plaques and A? Fibrillogenesis -- Transgenic Mouse Models for APP Processing and Alzheimer's Disease: Early and Late Defects -- Oxidative stress in Alzheimer's Disease: Implications for Prevention and Therapy --?-Secretase, APP and A? in Alzheimer's Disease -- The Non-Amyloidogenic Pathway: Structure and Function of?-Secretases -- Amyloid? Degradation: A Challenging Task for Brain Peptidases -- The Protective Role of Vitamin E in Vascular Amyloid?-Mediated Damage -- Amyloid Accumulation and Pathogensis of Alzheimer's Disease: Significance of Monomeric, Oligomeric and Fibrillar A? -- Cholesterol and Amyloid? Fibrillogenesis -- Alzheimer's?-Amyloid: Insights into Fibril Formation and Structure from Congo Red Binding -- The Aluminium-Amyloid Cascade Hypothesis and Alzheimer's Disease -- Amyloid-? Metal Interaction and Metal Chelation -- The Interaction of Amyloid-? with ApoE -- Clusterin and Alzheimer's Disease -- Acetylcholinesterase Interaction with Alzheimer Amyloid? -- Membrane Disordering Effects of?-Amyloid Peptides -- The Role of Alzheimer A? Peptides in Ion Transport Across Cell Membranes -- Amyloid Inhibitors and?-Sheet Breakers -- Cholesterol and Alzheimer's Disease: Statins, Cholesterol Depletion in APP Processing and A? Generation -- Phosphorylated Amyloid-?: the Toxic Intermediate in Alzheimer's Disease Neurodegeneration