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Status:
Available4.8
12 reviews
ISBN-10 : 0824709519
ISBN-13 : 9780824709518
Author: Reinhard H H Neubert, Hans Hermann Ruttinger
This reference presents the most recent breakthroughs and techniques in affinity capillary electrophoresis (ACE) to measure and determine the physicochemical and thermodynamic parameters of drug compounds. The authors offer strategies to explore and characterize interactions between drugs, drug vehicles, and biological membranes to facilitate developments in controlled drug delivery and targeting. The book contains current applications and procedures to identify binding constants between drugs, biological structures, proteins, nucleic acids, and plasmids, increase drug bioavailability, enhance the permeability, solubility, strength, and function of drug formulations, examine protein-protein exchanges and reactions, and calculate pKa values.
chapter 1 Principles of Capillary Electrophoresis
chapter 2 Theory of Affinity Electrophoresis
chapter 3 Determination of Physicochemical Parameters
chapter 4 Affinity of Drugs to Excipients
chapter 5 Affinity of Drugs to Pharmaceutical Vehicle Systems: Micelles
chapter 6 Affinity of Drugs to Pharmaceutical Vehicle Systems: Microemulsions
chapter 7 Interaction of Drugs with Liposomes and Proteoliposomes
chapter 8 Interactions Between Chiral Drugs and Cyclodextrins
chapter 9 Affinity of Drugs to Proteins and Protein-Protein Interactions
chapter 10 Affinity Capillary Electrophoresis: DNA Interactions with Peptides, Proteins, and Modified DNA
chapter 11 Characterization of Polysaccharide Interactions
chapter 12 Characterization of Immunoreactions
chapter 13 Hyphenation of Affinity Capillary Electrophoresis with Mass Spectrometry
chapter 14 Conclusions
immunoaffinity capillary electrophoresis
capillary electrophoresis interpretation
capillary electrophoresis proteins
affinity capillary electrophoresis (ace)
capillary electrophoresis binding constants
Tags: Affinity Capillary, Electrophoresis, Pharmaceutics, Biopharmaceutics, Reinhard Neubert, Hans Hermann Ruttinger
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