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Status:
Available5.0
38 reviews
ISBN-10 : 0123748321
ISBN-13 : 9780123748324
Author: Frederick W. Alt
Advances in Immunology, Volume 147, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology. Chapters in this new release include Histone deacetylases as targets in autoimmune and autoinflammatory diseases, The advancing area of the mechanisms involved in the evolution of HIV-1 neutralizing antibodies, T cells in latent viral infections, Communications of dendritic cells with T cells and NK cells in cancerous tissues, Mechanism and Regulation of Class Switch Recombination by IgH transcriptional Control Elements, IL-2 partial agonist, Preserving Immune Homeostasis with A20, The design of vaccine strategies to elicit HIV-1 broadly neutralizing antibodies.
Chapter One: Histone deacetylases as targets in autoimmune and autoinflammatory diseases
Abstract
1: Introduction
2: Basic aspects of the biology of HDACs
3: Rheumatoid arthritis
4: Inflammatory bowel diseases
5: Multiple sclerosis
6: Outlook
Acknowledgments
Chapter Two: The role of NK cell as central communicators in cancer immunity
Abstract
1: NK cells in cancer
2: NK cell cross-talk with innate immune cells
3: Cross-talk of NK cells with adaptive immune cells
4: Cross-talk of NK cell with stromal cells
5: Impairment of NK cell communication
6: Concluding remarks
Chapter Three: Mechanism and regulation of class switch recombination by IgH transcriptional control elements
Abstract
1: Overview of class switch recombination
2: Role of IgH transcriptional control elements
3: Class switch recombination in the CH12F3 cell line
4: Class switch recombination in developing B cells
5: Mechanism and regulation of class switch recombination
6: The lncCSRIgA locus
7: Perspectives
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Tags: Advances, Immunology, Frederick Alt, publication
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