Advances in cancer research. Volume 80 by Vande Woude, George F; Klein, George, 1928-1981 instant download

Advances in cancer research. Volume 80 by Vande Woude, George F; Klein, George, 1928-1981 instant download

1 online resource, Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here once again, outstanding and original reviews are presented on a variety of topics including platelet-derived growth factor in disease, genetic predisposition in tumor development, primary effusion lymphoma, and many more. Key Features* Involvement of Platelet-Derived Growth Factor in Disease: Development of Specific Antagonists* Tumor Suppression Activity of Adenovirus E1a Protein: Anoikis and the Epithelial Phenotype* Comparative Analysis of the Transforming Mechanisms of, Title from PDF title page (viewed September 27, 2007), Includes bibliographical references and index, Front Cover; Advances in Cancer Research; Copyright Page; Contents; Contributors to Volume 80; Chapter 1. Involvement of Platelet-Derived Growth Factor in Disease: Development of Specific Antagonists; I. Introduction; II. Platelet-Derived Growth Factor (PDGF) and PDGF Receptors; III. Intracellular Signal Transduction; IV. In Vivo Function of Pdgf; V. Pdgf in Disease; VI. Pdgf and Pdgf Receptors as Drug Targets; VII. Future Perspectives; References; Chapter 2. Tumor Suppression Activity of Adenovirus E1a Protein: Anoikis and the Epithelial Phenotype; I. Introduction, II. Historical Development of E1a as a Tumor SuppressorIII. Epithelial Conversion: Phenomenology; IV. Epithelial Conversion: Mechanisms; V. Anoikis Sensitization and Tumor Suppression by E1a; References; Chapter 3. Comparative Analysis of the Transforming Mechanisms of Epstein-Barr Virus, Kaposi's Sarcoma-Associated Herpesvirus, and Herpesvirus Saimiri; I. Introduction; II. Comparative Analysis of Gamma Herpesvirus Gene Products; III. Conclusion; References; Chapter 4. Genetic Predisposition and Somatic Diversification in Tumor Development and Progression; I. Introduction, II. Hereditary Colorectal Cancer SyndromesIII. Tumor Mutations and Molecular Clocks: Gateways to the Fourth Dimension;…