(Ebook) 5 HT2C Receptors in the Pathophysiology of CNS Disease 1st Edition by Jose M Palacios, Angel Pazos, Daniel Hoyer, Giuseppe Di Giovanni, Ennio Esposito, Vincenzo Di Matteo ISBN 1607619407 9781607619406

(Ebook) 5 HT2C Receptors in the Pathophysiology of CNS Disease 1st Edition by Jose M Palacios, Angel Pazos, Daniel Hoyer, Giuseppe Di Giovanni, Ennio Esposito, Vincenzo Di Matteo ISBN 1607619407 9781607619406

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ISBN 10: 1607619407 
ISBN 13: 9781607619406
Author: Jose M Palacios, Angel Pazos, Daniel Hoyer, Giuseppe Di Giovanni, Ennio Esposito, Vincenzo Di Matteo

Part of Springer’s “The Receptors,” series, this text is the first ever overview on the research of 5-HT2c receptors. 5-HT2c receptor research has been productive for twenty-five years, but recent years have seen an extraordinary increase in both amount produced and insight gained. 5-HT2c is a prominent central serotonin receptor subtype widely expressed within the central and the peripheral nervous system and is thought to play a key role in the regulation of numerous behaviors. This text covers the molecular, cellular, anatomical, biochemical and behavioral aspects of this receptor, highlighting its distinctive regulatory properties and the emerging functional significance of constitutive activity and RNA-editing in vivo. It also investigates the receptors’ therapeutic potential in many diseases, treated individually in separate chapters, including depression, drug abuse, schizophrenia, eating disorders, Parkinson’s disease, Prader-Willi Syndrome, Alzheimer’s disease and epilepsy.

(Ebook) 5 HT2C Receptors in the Pathophysiology of CNS Disease 1st Table of contents:

1. Chapter 1: The Making of the 5-HT2C Receptor
2. Chapter 2: Serotonin 5-HT2C Receptors: Chemical Neuronatomy in the Mammalian Brain
3. Chapter 3: The Medicinal Chemistry of 5-HT2CReceptor Ligands
4. Chapter 4: Insights into 5-HT2C Receptor Function Gained from Transgenic Mouse Models
5. Chapter 5: Serotonin 5-HT2C Receptor Signal Transduction
6. Chapter 6: Homology Modeling of 5-HT2C Receptors
7. Chapter 7: 5-HT2C Receptor Dimerization
8. Chapter 8: RNA Editing of 5-HT2C Receptor and Neuropsychiatric Diseases
9. Chapter 9: Serotonergic Control of Adult Neurogenesis: Focus on 5-HT2C Receptors
10. Chapter 10: The Constitutive Activity of 5-HT2C Receptors as an Additional Modality of Interactionof
11. Chapter 11: The 5-HT2C Receptor Subtype Controls Central Dopaminergic Systems: Evidence from Electro
12. Chapter 12: The Role of 5-HT2C Receptors in the Pathophysiology and Treatment of Depression
13. Chapter 13: 5-HT2C Receptors and Suicidal Behavior
14. Chapter 14: The 5-HT2C Receptor as a Target for Schizophrenia
15. Chapter 15: Serotonin and Reward-Related Behavior: Focus on 5-HT2C Receptors
16. Chapter 16: Tat-3L4F: A Novel Peptide for Treating Drug Addiction by Disrupting Interaction Between
17. Chapter 17: The Role of Serotonin in Eating Behavior: Focus on 5-HT2C Receptors
18. Chapter 18: Physiological and Pathophysiological Aspects of 5-HT2c Receptors in Basal Ganglia
19. Chapter 19: Modeling Tardive Dyskinesia: Predictive 5-HT2C Receptor Antagonist Treatment
20. Chapter 20: The Role of 5-HT2A/2C Receptors in Sleep and Waking
21. Chapter 21: Role of Alternative Splicing of the 5-HT2C Receptor in the Prader–Willi Syndrome
22. Chapter 22: The Role of 5-HT2C Receptor in Epilepsy
23. Chapter 23: The Role of Serotonin on Attentional Processes and Executive Functioning: Focus on 5-HT2
24. Chapter 24: 5-HT2C Receptors in Learning
25. Chapter 25: The Role of 5-HT2C Polymorphisms in Behavioral and Psychological Symptoms of Alzheimer D
26. Chapter 26: Ocular Hypotension: Involvement of Serotonergic 5-HT2 Receptors

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Tags: Jose M Palacios, Angel Pazos, Daniel Hoyer, Giuseppe Di Giovanni, Ennio Esposito, Vincenzo Di Matteo, HT2C, Receptors